R26-CAG-Luc-2A-EGFP
Nomenclature
C57BL/6JSmo-Gt(ROSA)26Sorem1(CAG-Luc-EGFP)Smoc
Cat. NO.
NM-KI-00087
Strain State
Repository Live
Gene Summary
Gene Symbol
Gt(ROSA)26Sor
Model Description
Validation Data
Fig 1. Bioluminescence imaging of the whole body in R26-(Luc-EGFP) knockin mice.
Fig 2. Bioluminescence imaging of the main organ in R26-(Luc-EGFP) knockin mice.
Fig3. Comparison of EGFP expression in various organs.
Fig4. Comparison of EGFP expression in PB/BM/SP/THY.
Fig.1 Luciferase expression in R26-CAG-Luc-2A-EGFP transgenic mice and WT C57BL/6 mice by using in vivo bioluminescence imaging (IVIS). IVIS imaging demonstrated significantly elevated bioluminescent signals in R26-CAG-Luc-2A-EGFP mice compared to wild-type (WT) C57BL/6 mice, which displayed minimal bioluminescence signal under the same imaging conditions. Following intraperitoneal injection of D-luciferin substrate in anesthetized mice, bioluminescent photon emission signals were captured and quantified (n=3, female, 15 weeks old).
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