Stat3-KO(in-frame mutation)

Nomenclature

C57BL/6JSmo-Stat3emSmoc

Cat. NO.

NM-KO-210186

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Stat3

Synonyms

Aprf; AW109958; 1110034C02Rik

Chromosome

11

NCBI ID

20848

MGI ID

103038

Ensembl ID

ENSMUSG00000004040

Pubmed

Stat3

Human Ortholog

STAT3

Model Description

exon 18-20 of Stat3 gene was deleted to generate Stat3 knockout mice. The targeted knockout region mirrors that of the NM-CKO-200225 strain, with the experimental strategy designed according to published methodologies (PMID: 14566054; 17660847; 12571365).Lethality associated with this genetic modification has been documented. For details, click on the MGI ID in the genetic information.

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more

Workshop：Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more