hSOST

Nomenclature

C57BL/6JSmo-Sosttm1(hSOST)Smoc

Cat. NO.

NM-HU-200251

Strain State

Repository Live

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Gene Summary

Gene Symbol
Sost

Model Description

The endogenous mice Sost gene was replaced by human SOST gene. While hSOST(2)(Stock No.NM-HU-215021) mice function similarly to hSOST mice, for more detailed information please contact our technical advisor.

Validation Data

image.png

Fig.1 Detection of SOST expression in heart by RT-PCR. 

Wild type: only one band at 195 bp with primers F1/R1 (mSost);

Homozygous: only one band at 138 bp with primers F2/R2 (hSOST); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hSOST expression in plasma by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.


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