Cpa1-N256K
Nomenclature
Cat. NO.
Strain State
Model Description
Validation Data
Fig1. The pancreas of a heterozygous female mouse with Cpa1 N256K mutation.
The pancreas of 13.5-week-old Cpa1 N256K heterozygous female mice exhibited typical morphological changes, including acinar loss, inflammatory cell infiltration, acinar-ductal metaplasia, fibrosis, and some acinar cells showing vacuolation .The scale bar corresponds to 100 µm.
Pathology scores: 0 represents within the normal range, 1 represents mild, 2 represents moderate, and 3 represents marked
Fig2. The pancreas of a heterozygous male mouse with Cpa1 N256K mutation
The pancreatic tissue of 6-week-old and 13.5-week-old Cpa1 N256K heterozygous male mice showed a loss of acinar cells, accompanied by infiltration of inflammatory cells, acinar-ductal metaplasia, fibrosis changes, and partial vacuolation of acinar cells.The scale bar corresponds to 100 µm.
Pathology scores: 0 represents within the normal range, 1 represents mild, 2 represents moderate, and 3 represents marked
You may also like
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreCustomizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn moreMilestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
