Inmt-Cre-2A-H2B-tdTomato

Nomenclature

C57BL/6JSmo-Inmtem1(Kozak-Cre-2A-H2B-tdTomato-WPRE-pA)Smoc

Cat. NO.

NM-KI-231153

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Inmt

Model Description

The Kozak-Cre-2A-H2B-tdTomato-WPRE-pA expression cassette was knocked into the Inmt gene start codon site.

Validation Data

image.png

Fig1. Cre mediated recombination in the brain of InmtCre-2A-H2B-tdTomato/+;Rosa26 zsGreen/+ mice.


Inmt-Cre-2A-H2B-tdTomato.jpg

Fig2. Detection of tdTomato(red) and zsGreen(green) in various tissues of InmtCre-2A-H2B-tdTomato/+;Rosa26 zsGreen/+ mice.

Male:The tdTomato reporter gene is expressed in the lung, eyeball, liver, spinal cord, stomach, salivary gland, skin, kidney, large intestine, prostate, thymus, and pituitary gland; it is expressed at low levels in the brain and heart; no significant expression is observed in the spleen or testis. The zsGreen reporter gene is expressed in the brain, spinal cord, eyeball, heart, lung, liver, stomach, salivary gland, skin, kidney, large intestine, small intestine, spleen, prostate, testis, thymus, and pituitary gland.Mouse age: 84 days, Male.

Female:The tdTomato reporter gene is expressed in the lung, eyeball, spinal cord, liver, stomach, salivary gland, skin, kidney, large intestine, vagina, thymus, and pituitary gland; it is expressed at low levels in the brain, heart, and small intestine; no significant expression is observed in the spleen, ovary, or fallopian tube. The zsGreen reporter gene is expressed in the brain, eyeball, spinal cord, heart, lung, liver, stomach, salivary gland, skin, kidney, large intestine, small intestine, spleen, vagina, ovary, fallopian tube, thymus, and pituitary gland.Mouse age: 84 days, Female.

 (For more detailed information please contact our technical advisor.) 




You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more