Tmem173-KO

Nomenclature

C57BL/6JSmo-Tmem173em1Smoc

Cat. NO.

NM-KO-2105967

Strain State

Repository Live

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Model Description

Exon 4-6 of Tmem173 gene was deleted to generate Tmem173 knockout mice.

Validation Data

image.png

Fig.1 Detection of mouse Tmem173 expression in the female C57BL/6 WT mouse (8-10 weeks old) and Tmem173-KO mice (9 weeks old) by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.

2d6c847bf2260a7b321db822a8e6d279.png

Fig.2 Detection of TMEM173 expression in Tmem173-KO mice by WB. TMEM173 was exclusively detectable in heart from WT C57BL/6 mice with a mouse TMEM173 antibody. The heart tissue lysates were collected from 13-week-old female wild-type C57BL/6 mice and 13-week-old female homozygous Tmem173-KO mice, and then analyzed by western blot with anti-TMEM173 antibody. 

Abbr. HO, homozygous; WT, wild type.


Publications 1piece

1. Glycolysis drives STING signaling to facilitate dendritic cell antitumor function
Published year:2023-04-03 References:JCI

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