Dppa3-IRES-Cre

Nomenclature

C57BL/6JSmo-Dppa3em1(IRES-Cre)Smoc

Cat. NO.

NM-KI-00040

Strain State

Repository Live

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Gene Summary

Gene Symbol
Dppa3

Model Description

The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.
Research Application:Dppa3 (also known as Pgc7 or Stella) plays an important role in early embryonic development during the cleavage stage as a maternal effect gene.

Validation Data

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Fig. 1 Detection of Zsgreen(green) in various tissues of Dppa3Cre/+; Rosa26Zsgreen/+mice. Zsgreen expression can be detected in the brain, heart, lung, submandibular gland, salivary gland, stomach, kidney, pancreas, testis, epididymis, colon and spleen of Dppa3Cre/+; Rosa26Zsgreen/+mouse. (For more detailed information please contact our technical advisor.)

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Fig. 2 Cre-mediated recombination in the E14.5 Dppa3Cre/+; Rosa26tdTomato/+ mouse embryos. 


Publications 1piece

1. Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
Published year:2022-03-22 References:Nature Communications

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