R26-CAG-Cas9
Nomenclature
C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Cat. NO.
NM-KI-00120
Strain State
Repository Live
Gene Summary
Gene Symbol
Gt(ROSA)26Sor
Model Description
Validation Data
Fig1. Analysis of Cas9 expression profile by Western Blot. The CAG-Cas9 KI mice express Cas9 in heart, liver, spleen, lung, kidney, stomach, cortex, cerebellum, testis and muscle.
J***: Cas9 KI mice from other peers
CAG-Cas9: R26-CAG-Cas9 mice (NM-KI-00120) obtained by R26-CAG-LNL-Cas9(NM-KI-00038) crossed with Ella-Cre
Cas9-krab: R26-CAG-3XKRAB-dCas9-IRES-EGFP（NM-KI-18007）
Fig2. Detection of CAS9 expression in R26-CAG-CAS9 mice by WB.
Abbr. M, marker; WT, wild type; HO, homozygous; WAT, white adipose tissue; BAT, brown adipose tissue.
Note. 60 μg of total protein were loaded for BAT and skeletal muscle, and 20 μg for other tissues.
Fig.3 Detection of CAS9 expression in T cells in R26-CAG-CAS9 mice by WB.
Abbr. M, marker; WT, wild type; HO, homozygous.
You may also like
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreCustomizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn moreMilestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
