Col1a1-IRES-CreERT2

Nomenclature

C57BL/6JSmo-Col1a1em(IRES-CreERT2)1Smoc

Cat. NO.

NM-KI-225031

Strain State

Repository Live

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Gene Summary

Gene Symbol
Col1a1

Model Description

IRES-CreERT2 expression cassette was knocked into the Col1a1 gene. The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.
Research Application:Cre mouse,osteoblast

Validation Data

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Fig1. Cre mediated recombination in femur of Col1a1CreERT2/+;Rosa26tdTomato/+ mouse. 

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Fig2. Detection of tdTomato(red) in various tissues of Col1a1CreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: lung, stomach, teeth, pancreas, small intestine, colon, spleen, epididymis, skin, pituitary gland and skull. A few cells expressed in brain, eyeball, heart, liver, salivary gland, adrenal gland, kidney, muscle, thymus. Tissues that unexpressed include spinal cord, brown fat.The control group is expressed before induction. (39-days old, male) (For more detailed information please contact our technical advisor.) 


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