Slc17a8-IRES-Cre

Nomenclature

C57BL/6JSmo-Slc17a8em1(IRES2-iCre)Smoc

Cat. NO.

NM-KI-200085

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Slc17a8

Model Description

A IRES2-iCre expression cassette was knocked into the Slc17a8 gene stop codon site.
Research Application:Cre recombinase tool, Vglut3-expressing cells

Validation Data

841a7d7a-1dd0-42c4-a624-837eb93bd995.png

Fig1. Cre mediated recombination in spinal cord of Slc17a8Cre/+;Rosa26 tdTomato/+ mice.

5ccb9fec-8beb-40e1-937b-d4a6c6c6a49f.png

Fig2. Detection of tdTomato(red) in various tissues of Slc17a8Cre/+; Rosa26 tdTomato/+mice.

Female tdTomato fluorescence-expressing tissues include: brain, spinal cord, eyeballs, heart, lungs, liver, stomach, muscle, skin, kidneys, colon, intestine, thymus, spleen, reproductive system, pancreas, and dorsal root ganglia. No obvious tdTomato fluorescence was detected in the adrenal glands. Mouse age: 36 days; Female.

Male tdTomato fluorescence-expressing tissues include: brain, spinal cord, eyeballs, heart, lungs, liver, stomach, muscle, skin, kidneys, colon, intestine, thymus, spleen, reproductive system, pancreas, and dorsal root ganglia. No obvious tdTomato fluorescence was detected in the adrenal glands. Mouse age: 36 days; Male.


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more