Products
U-GEMMs

Toolbox of Mice

Find Cre

Reporters

Target Humanized Knockins

Tumor Targets

Immune Checkpoints

Complements

Cytokines

Cytokine Receptors

Metabolic Targets

Viral Infection Receptors

Other Targets

Disease Mice

Spontaneous Tumor

Rare Disease

Infectious Disease

Nervous System Disease

Cardio-metabolic Disease

Autoimmune Disease

Immune-Related Mice

Humanized Drug Targets

Immunodeficient

Cytokine Reporters

Inducible Cell Ablation

Cell-specific Reporters

Popular Strains

Humanized PD-1 Mice

Humanized PD-L1 Mice

NMG Mice

Other Models

Rats

Humanized Drug Targets

Immunodeficient

Diseases

Reporters

Cre-drivers

Standard Strains

Inbred

Outbred

Cells

Reporter-labeled

Primary

Humanized Drug Targets

Wild-type

Others

Model Customization

Gene Editing Technology

ES Cell Targeting

CRISPR Gene Editing

Transgene

Genetically Engineered Type

Conventional Knockout (KO)

Conditional Knockout (CKO)

KO First

Knock-in (KI)

Point Mutation

Conditional Point Mutation

Humanization

Targeted Conditional Overexpression

Random Transgene

Surgery & Preconditioning

Surgery

Preconditioning

Supporting Solutions

Colony Management

Cryopreservation and Cryorecovery

Housing and Management

Genotyping Analysis

Breeding Services

Auxiliary Apparatuses

e-BLOT WB Imaging System
Pre-clinical CRO Services
Oncology Drug Efficacy Evaluation Platform

Syngeneic Models

Genetically Modified Tumor Mouse Models

GMM models of cancer

GMM-derived tumor allograft models

Xenograft mouse models

CDX

PDX

Human Immune System Reconstituted Models

HuPBMC

HuHSC

Metabolism Disease Evaluation Platform

Obesity/Diabetes Models

MASH Model

Other metabolic disease models

Hyperuricemia Models

Atherosclerosis Models

Phenylketonuria Models

Humanized Metabolic Research Model

Inflammation Disease Evaluation Platform

Inflammation/Autoimmune Disease Model

Psoriasis model

Atopic Dermatitis Model

Delayed-type hypersensitivity Model

Androgenetic Alopecia Model

Asthma Model

Pulmonary Fibrosis Model

Rheumatoid Arthritis Model

Osteoarthritis Model

Systemic Lupus Erythematosus Model

Sepsis Model

Multiple Sclerosis Model

Graft-Versus-Host Disease Model

Inflammatory Bowel Disease Model

Chronic Kidney Disease Model

Others immune-mediated inflammatory diseases model

Neurological Disease Evaluation Platform

Neurological Disease Models

Parkinson's Disease Model

Alzheimer's Disease Model

Depression Model

Pain Model

Cerebrovascular Diseases Model

Intracranial Tumor

Amyotrophic Lateral Sclerosis Model

Other Neurological Disease Models

Behavioral Research Platform

Cell Lines Service Platform

Off-the-shelf cell lines

iPSC-mediated Disease Models

Cell Line Customization Services

Ex vivo & In vitro Evaluation Service Platform

Ex vivo Pharmacodynamic Evaluation Service

In vitro Pharmacodynamic Evaluation Service

Toxicology/Pathology Service Platform

Non-GLP Toxicology Evaluation Platform

Pathology Service Platform
Resources & Support
Resources

Literature Library

Model Publications

Health Reports

External Resources

Support

Search for Mice

Search for Publications

Frequently Asked Questions (FAQ)

Applications
About Us
SMOC

Who We are

Credentials

Milestones

Payment Information
Investor Relations

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

Mouse	kif18A-KO Strain Name：B6;129S-kif18A^tm1Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-00008 Research Application：male infertility，orchiatrophy，azoospermia
Mouse	Kmt2b-Flox Strain Name：C57BL/6JSmo-Kmt2b^{tm1(flox)Smoc} Strain State：Repository Live \| Cat. NO.：NM-CKO-190029 Research Application：Epigenetic
Mouse	KPC Strain Name：C57BL/6JSmo-Trp53^em4(R172H)Kras^{em4(LSL-G12D)}Tg(Pdx1-cre)Smoc Strain State：Repository Live \| Cat. NO.：NM-KI-210096 Disease Connection：pancreatic carcinoma
Mouse	KPC(2) Strain Name：C57BL/6JSmo-Trp53^{tm7(R270H-flox})Kras^{em4(LSL-G12D)}Tg(Pdx1-cre)Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-220014 Disease Connection：pancreatic carcinoma
Mouse	KPC(3) Strain Name：C57BL/6JSmo-Kras^{em4(LSL-G12D)}Trp53^{tm(LSL-R172H)}Tg(Pdx1-Cre)Smoc Strain State：Repository Live \| Cat. NO.：NM-KI-234804
Mouse	Kras-LSL-G12D Strain Name：C57BL/6JSmo-Kras^{em4(LSL-G12D)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-190003 Disease Connection：squamous cell carcinoma, prostate cancer, pancreatic carcinoma, neurofibromatosis, pancreatic ductal adenocarcinoma, juvenile myelomonocytic leukemia, urinary bladder cancer, ovarian cancer
Mouse	Lat-Y136F Strain Name：C57BL/6JSmo-Lat^{em1(Y136F）Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-200249 Disease Connection：IgG4-related disease
Mouse	Ldb3-Flox Strain Name：C57BL/6JSmo-Ldb3^{em1(flox)Smoc} Strain State：Repository Live \| Cat. NO.：NM-CKO-253977 Disease Connection：dilated cardiomyopathy 1C
Mouse	Ldlr-KO(2) Strain Name：C57BL/6JSmo-Ldlr^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-210198 Disease Connection：familial hypercholesterolemia, fatty liver disease
Mouse	Lep-KO Strain Name：B6;129S-Lep^tm1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-00034 Disease Connection：abdominal obesity-metabolic syndrome, abdominal obesity-metabolic syndrome 1, non-alcoholic fatty liver disease, obesity, type 2 diabetes mellitus

Items per page

Contact Back to top