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Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

Mouse	Nos1-KO Strain Name：C57BL/6JSmo-Nos1^em¹^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-240406 Disease Connection：hypertrophic cardiomyopathy, nephrogenic diabetes insipidus, achalasia, hypertrophic pyloric stenosis
Mouse	Nos3-KO Strain Name：C57BL/6JSmo-Nos3^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-18022 Disease Connection：hypertrophic cardiomyopathy, nephrogenic diabetes insipidus, essential hypertension, persistent fetal circulation syndrome
Mouse	Notch3-R170C Strain Name：C57BL/6JSmo-Notch3^{em1(R170C)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-200254 Disease Connection：CADASIL 1
Mouse	Npc1-Flox Strain Name：C57BL/6JSmo-Npc1^{em2(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-200070 Disease Connection：Niemann-Pick disease
Mouse	Nphs2-A286V Strain Name：C57BL/6JSmo-Nphs2^{em1(A286V)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-200278 Disease Connection：hereditary glomerular disease
Mouse	Nphs2-R231Q Strain Name：C57BL/6JSmo-Nphs2^{em1(R231Q)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-200277 Disease Connection：hereditary glomerular disease
Mouse	Nppa-KO Strain Name：C57BL/6Smoc-Nppa^em1Smoc Strain State：Developing \| Cat. NO.：TBD Disease Connection：hypertension
Mouse	Npy1r-KO Strain Name：C57BL/6JSmo-Npy1R^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-190999 Disease Connection：obesity
Mouse	Nr5a1-Flox Strain Name：C57BL/6JSmo-Nr5a1^{em1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-200071 Disease Connection：hypogonadotropic hypogonadism
Mouse	Nrcam-KO Strain Name：C57BL/6Smoc-Nrcam^em1Smoc Strain State：Developing \| Cat. NO.：TBD Disease Connection：autism spectrum disorder

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