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U-GEMMs

Toolbox of Mice

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Spontaneous Tumor

Rare Disease

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Humanized Drug Targets

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Popular Strains

Humanized PD-1 Mice

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Model Customization

Gene Editing Technology

ES Cell Targeting

CRISPR Gene Editing

Transgene

Genetically Engineered Type

Conventional Knockout (KO)

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KO First

Knock-in (KI)

Point Mutation

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Humanization

Targeted Conditional Overexpression

Random Transgene

Surgery & Preconditioning

Surgery

Preconditioning

Supporting Solutions

Colony Management

Cryopreservation and Cryorecovery

Housing and Management

Genotyping Analysis

Breeding Services

Auxiliary Apparatuses

e-BLOT WB Imaging System
Pre-clinical CRO Services
Oncology Drug Efficacy Evaluation Platform

Syngeneic Models

Genetically Modified Tumor Mouse Models

GMM models of cancer

GMM-derived tumor allograft models

Xenograft mouse models

CDX

PDX

Human Immune System Reconstituted Models

HuPBMC

HuHSC

Metabolism Disease Evaluation Platform

Obesity/Diabetes Models

MASH Model

Other metabolic disease models

Hyperuricemia Models

Atherosclerosis Models

Phenylketonuria Models

Humanized Metabolic Research Model

Inflammation Disease Evaluation Platform

Inflammation/Autoimmune Disease Model

Psoriasis model

Atopic Dermatitis Model

Delayed-type hypersensitivity Model

Androgenetic Alopecia Model

Asthma Model

Pulmonary Fibrosis Model

Rheumatoid Arthritis Model

Osteoarthritis Model

Systemic Lupus Erythematosus Model

Sepsis Model

Multiple Sclerosis Model

Graft-Versus-Host Disease Model

Inflammatory Bowel Disease Model

Chronic Kidney Disease Model

Others immune-mediated inflammatory diseases model

Neurological Disease Evaluation Platform

Neurological Disease Models

Parkinson's Disease Model

Alzheimer's Disease Model

Depression Model

Pain Model

Cerebrovascular Diseases Model

Intracranial Tumor

Amyotrophic Lateral Sclerosis Model

Other Neurological Disease Models

Behavioral Research Platform

Cell Lines Service Platform

Off-the-shelf cell lines

iPSC-mediated Disease Models

Cell Line Customization Services

Ex vivo & In vitro Evaluation Service Platform

Ex vivo Pharmacodynamic Evaluation Service

In vitro Pharmacodynamic Evaluation Service

Toxicology/Pathology Service Platform

Non-GLP Toxicology Evaluation Platform

Pathology Service Platform
Resources & Support
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U-GEMMs

The establishment of U-GEMM (yoUr Genetically Engineered Mouse Model) repository containing 6,000+ “off-shelf” proprietary sets the stage of entry into new possibilities in gene function, drug screening, and human disease research.

Mouse	hB7H3/hCD28 Strain Name：C57BL/6JSmo-Cd276^tm2(hCD276)Cd28^{tm2(hCD28)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-210353 Research Application：inmmue therapy；drug screening
Mouse	hB7H3/hPD-1 Strain Name：C57BL/6JSmo-Cd276^tm2(hCD276)Pdcd1^{tm1(hPDCD1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-210349 Research Application：inmmue therapy；drug screening
Mouse	hB7H4 Strain Name：C57BL/6JSmo-Vtcn1^{tm1(hVTCN1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-190004 Research Application：Immune-related
Mouse	hB7H4(2) Strain Name：C57BL/6JSmo-Vtcn1^{tm2(hVTCN1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-190075 Research Application：Immunotherapy,Cancer research,Drug screening
Mouse	Hba-a1-Flox Strain Name：C57BL/6Smoc-Hba-a1^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Hba-a2-Flox Strain Name：C57BL/6JSmo-Hba-a2^em^1(flox)^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-241612
Mouse	Hba-a2-KO Strain Name：C57BL/6JSmo-Hba-a2^em¹^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-251458
Mouse	Hba-x-Flox Strain Name：C57BL/6Smoc-Hba-x^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	hBACE1 Strain Name：C57BL/6JSmo-Bace1^{tm(hBACE1)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-220263
Mouse	hBAFF(BALB/c) Strain Name：BALB/cJSmo-Igs2^{tm1(pAlb-hTNFSF13B-3'UTR var-polyA)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-252776

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