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U-GEMMs

Toolbox of Mice

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Target Humanized Knockins

Tumor Targets

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Complements

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Spontaneous Tumor

Rare Disease

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Humanized Drug Targets

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Cytokine Reporters

Inducible Cell Ablation

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Popular Strains

Humanized PD-1 Mice

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NMG Mice

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Rats

Humanized Drug Targets

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Humanized Drug Targets

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Model Customization

Gene Editing Technology

ES Cell Targeting

CRISPR Gene Editing

Transgene

Genetically Engineered Type

Conventional Knockout (KO)

Conditional Knockout (CKO)

KO First

Knock-in (KI)

Point Mutation

Conditional Point Mutation

Humanization

Targeted Conditional Overexpression

Random Transgene

Surgery & Preconditioning

Surgery

Preconditioning

Supporting Solutions

Colony Management

Cryopreservation and Cryorecovery

Housing and Management

Genotyping Analysis

Breeding Services

Auxiliary Apparatuses

e-BLOT WB Imaging System
Pre-clinical CRO Services
Oncology Drug Efficacy Evaluation Platform

Syngeneic Models

Genetically Modified Tumor Mouse Models

GMM models of cancer

GMM-derived tumor allograft models

Xenograft mouse models

CDX

PDX

Human Immune System Reconstituted Models

HuPBMC

HuHSC

Metabolism Disease Evaluation Platform

Obesity/Diabetes Models

MASH Model

Other metabolic disease models

Hyperuricemia Models

Atherosclerosis Models

Phenylketonuria Models

Humanized Metabolic Research Model

Inflammation Disease Evaluation Platform

Inflammation/Autoimmune Disease Model

Psoriasis model

Atopic Dermatitis Model

Delayed-type hypersensitivity Model

Androgenetic Alopecia Model

Asthma Model

Pulmonary Fibrosis Model

Rheumatoid Arthritis Model

Osteoarthritis Model

Systemic Lupus Erythematosus Model

Sepsis Model

Multiple Sclerosis Model

Graft-Versus-Host Disease Model

Inflammatory Bowel Disease Model

Chronic Kidney Disease Model

Others immune-mediated inflammatory diseases model

Neurological Disease Evaluation Platform

Neurological Disease Models

Parkinson's Disease Model

Alzheimer's Disease Model

Depression Model

Pain Model

Cerebrovascular Diseases Model

Intracranial Tumor

Amyotrophic Lateral Sclerosis Model

Other Neurological Disease Models

Behavioral Research Platform

Cell Lines Service Platform

Off-the-shelf cell lines

iPSC-mediated Disease Models

Cell Line Customization Services

Ex vivo & In vitro Evaluation Service Platform

Ex vivo Pharmacodynamic Evaluation Service

In vitro Pharmacodynamic Evaluation Service

Toxicology/Pathology Service Platform

Non-GLP Toxicology Evaluation Platform

Pathology Service Platform
Resources & Support
Resources

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U-GEMMs

The establishment of U-GEMM (yoUr Genetically Engineered Mouse Model) repository containing 6,000+ “off-shelf” proprietary sets the stage of entry into new possibilities in gene function, drug screening, and human disease research.

Mouse	hPD-1/hPD-L1/hPD-L2 Strain Name：C57BL/6JSmo-Pdcd1lg2^{tm1(hPDCD1LG2)}Pdcd1^tm1(hPDCD1)Cd274^{tm1(hPD-L1)/Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-190060 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hPD-1/hPD-L1/hTACSTD2 Strain Name：C57BL/6JSmo-Pdcd1^{tm1(hPDCD1)Cd274tm1(hPD-L1)}Tacstd2^tm(hTACSTD2)^Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-XA-242246
Mouse	hPD-1/hPD-L1/hTIGIT Strain Name：C57BL/6JSmo-Pdcd1^tm1(hPDCD1)Cd274^tm1(hPD-L1)Tigit^{tm1(hTIGIT)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-200267
Mouse	hPD-1/hPD-L1/hTIM3 Strain Name：C57BL/6JSmo-Pdcd1^tm1(hPDCD1)Cd274^tm1(hPD-L1)Havcr2^{tm1(hHAVCR2)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-200264
Mouse	hPD-1/hPVRIG Strain Name：C57BL/6JSmo-Pdcd1^tm1(hPDCD1)Pvrig^tm1(hPVRIG)^Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-231147
Mouse	hPD-1/hSEMA4D Strain Name：C57BL/6JSmo-Pdcd1^tm1(hPDCD1)Sema4d^{tm1(hSemA4D)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-190033 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hPD-1/hSIGLEC15 Strain Name：C57BL/6JSmo-Pdcd1^tm1(hPDCD1)Siglec15^{tm1(hSIGLEC15)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-2000093 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hPD-1/hSIRPA(2) Strain Name：C57BL/6JSmo-Pdcd1^tm1(hPDCD1)Sirpa^{tm2(hSIRPA)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-2000089 Research Application：Immunotherapy,drug screening
Mouse	hPD-1/hSTING Strain Name：C57BL/6JSmo-Tmem173^{tm1(hTMem173)}Pdcd1^{tm1(hPDCD1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-2000104 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hPD-1/hTIGIT Strain Name：C57BL/6JSmo-Pdcd1^tm1(hPDCD1)Tigit^{tm1(hTIGIT)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-00104 Research Application：Immunotherapy,cancer research,drug screening

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