Il4-Luc-2A-EGFP
Nomenclature
C57BL/6JSmo-Il4em1(Luc-eGFP)Smoc
Cat. NO.
NM-KI-00021
Strain State
Repository Live
Gene Summary
Gene Symbol
Il4
Model Description
Validation Data
Fig1. Time course of mean fluorescence intensity on the ventral of Il4-Luc-2A-EGFP mice after 12 mg/mL Con.A administration.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Individual fluorescence intensity on the ventral (A) and dorsal (B) of Il4-Luc-2A-EGFP mice treated with Con.A.
Fig.3 Detection of EGFP expression in spleen of WT C57BL/6 mice and IL4-Luc-2A-EGFP mice by FACS. EGFP was exclusively detectable in IL4-Luc-2A-EGFP mice but not in wild-type mice.Leukocytes were collected from wild-type mice (female,6 weeks old) and IL4-Luc-2A-EGFP mice.The WT mice with number 2 and IL4-Luc-2A-EGFP mice with number 7 and number 9 were injected with ConA (12mg/kg) by i.p. for 24 hours.
Abbr. HO, homozygous; WT, wild type.
Fig.4 Detection of EGFP expression in spleen of WT C57BL/6 mice and IL4-Luc-2A-EGFP mice by FACS.EGFP was exclusively detectable in IL4-Luc-2A-EGFP mice but not in wild-type mice.Leukocytes were collected from wild-type mice (female,6 weeks old) and IL4-Luc-2A-EGFP mice.The WT mice with number 2 and IL4-Luc-2A-EGFP mice with number 7 and number 9 were injected with ConA (12mg/kg) by i.p. for 24 hours.
Abbr. HO, homozygous; WT, wild type.
Fig.5 Detection of EGFP expression in lung of WT C57BL/6 mice and IL4-Luc-2A-EGFP mice by FACS. EGFP was exclusively detectable in IL4-Luc-2A-EGFP mice but not in wild-type mice.Leukocytes were collected from wild-type mice (female,6 weeks old) and IL4-Luc-2A-EGFP mice.The WT mice with number 2 and IL4-Luc-2A-EGFP mice with number 7 and number 9 were injected with ConA (12mg/kg) by i.p. for 24 hours.
Abbr. HO, homozygous; WT, wild type.
Fig.6 Detection of EGFP expression in lung of WT C57BL/6 mice and IL4-Luc-2A-EGFP mice by FACS.EGFP was exclusively detectable in IL4-Luc-2A-EGFP mice but not in wild-type mice.Leukocytes were collected from wild-type mice (female,6 weeks old) and IL4-Luc-2A-EGFP mice.The WT mice with number 2 and IL4-Luc-2A-EGFP mice with number 7 and number 9 were injected with ConA (12mg/kg) by i.p. for 24 hours.
Abbr. HO, homozygous; WT, wild type.
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