hPNPLA3
Nomenclature
C57BL/6JSmo-Pnpla3tm1(hPNPLA3)Smoc
Cat. NO.
NM-HU-241421
Strain State
Embryo Cryopreservation
Gene Summary
Gene Symbol
Pnpla3
Model Description
Validation Data
Fig.1 Detection of PNPLA3 expression in liver and mammary gland by RT-PCR.
Wild type: only one band at 178 bp with primers F1/R1(mPnpla3);
Homozygous: only one band at 146 bp with primers F2/R2(hPNPLA3).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of PNPLA3 expression in hPNPLA3 mice by WB. PNPLA3 was detectable in liver from both WT C57BL/6 and HO hPNPLA3 mice , as the antibody was cross-reactived between human and mouse PNPLA3. The liver tissue lysates were collected from 21-week-old male wild-type C57BL/6 mice and 21-week-old male homozygous hPNPLA3 mice, and then analyzed by western blot with anti-PNPLA3 antibody.
Abbr. HO, homozygous; WT, wild type; PC, positive control, liver tissue lysates.
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