Il6-2A-DTR-2A-EGFP
Nomenclature
C57BL/6JSmo-Il6em1(P2A-DTR-T2A-EGFP-WPRE-pA)Smoc
Cat. NO.
NM-KI-242149
Strain State
Sperm cryopreservation
Gene Summary
Gene Symbol
IL6
Model Description
Validation Data
Fig.1 Detection of EGFP expression in blood macrophages of Il6-2A-DTR-2A-EGFP mice by FACS.
Il6-2A-DTR-2A-EGFP mice that received an intraperitoneal dose of LPS (5 mg/kg) and were sacrificed 2 h later exhibited a pronounced increase of EGFP+ signals in blood (n=2, male, 6 weeks old).
Abbr. HE, heterozygous; WT, wild type.
Fig.2 Detection of EGFP expression in bone marrow macrophages of Il6-2A-DTR-2A-EGFP mice by FACS.
Il6-2A-DTR-2A-EGFP mice that received an intraperitoneal dose of LPS (5 mg/kg) and were sacrificed 2 h later exhibited a pronounced increase of EGFP+ signals in bone marrow (n=2, male, 6 weeks old).
Abbr. HE, heterozygous; WT, wild type.
Fig.3 Detection of EGFP expression in spleen macrophages of Il6-2A-DTR-2A-EGFP mice by FACS.
Il6-2A-DTR-2A-EGFP mice that received an intraperitoneal dose of LPS (5 mg/kg) and were sacrificed 2 h later exhibited a pronounced increase of EGFP+ signals in spleen (n=2, male, 6 weeks old).
Abbr. HE, heterozygous; WT, wild type.
Fig.4 Detection of EGFP expression in liver macrophages of Il6-2A-DTR-2A-EGFP mice by FACS.
Il6-2A-DTR-2A-EGFP mice that received an intraperitoneal dose of LPS (5 mg/kg) and were sacrificed 2 h later exhibited a pronounced increase of EGFP+ signals in liver (n=2, male, 6 weeks old).
Abbr. HE, heterozygous; WT, wild type.
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