hITGA4

Nomenclature

C57BL/6JSmo-Itga4em1(hITGA4)Smoc

Cat. NO.

NM-HU-225044

Strain State

Repository Live

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Gene Summary

Gene Symbol
Itga4

Model Description

The endogenous mouse Itga4 gene was replaced by human ITGA4 gene.

Validation Data

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Fig.1 Detection of ITGA4 expression on monocytes, DCs, NK cells in spleen of WT C57BL/6 mice and HO hITGA4 mice by FACS. Leukocytes were collected from spleen of wild-type C57BL/6 mice (male, 8 weeks old) and homozygous hITGA4 humanized mice (male, 8 weeks old), and analyzed by flow cytometry with anti-mCD49d and anti-hCD49d. 

Abbr. HO, homozygous; WT, wild type.


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