hMET

Nomenclature

C57BL/6JSmo-Mettm(hMET)Smoc

Cat. NO.

NM-HU-220342

Strain State

Repository Live

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Gene Summary

Gene Symbol
Met

Model Description

The endogenous mouse Met gene was replaced by human MET gene.

Validation Data


Fig.1 Detection of MET expression in kidney and lung by RT-PCR. Kidney RNA was extracted from 15-week-old female wild-type C57BL/6 (WT)(n=2) and heterozygous hMET knockin mice (HE) (n=3), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers. Abbr. M, marker; HE, heterozygous; WT, wild type.

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Fig.2 Detection of MET expression in hMET mice by WB. The liver, lung and kidney lysates were collected from 15-week-old female wild-type C57BL/6 mice and 15-week-old female heterozygous hMET mice, and then analyzed by western blot with anti-MET antibody (abcam, ab51067). Abbr. HE, heterozygous; WT, wild type; PC, positive control, Hela cells.


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