hCD2
Nomenclature
C57BL/6JSmo-Cd2tm1(hCD2)Smoc
Cat. NO.
NM-HU-204986
Strain State
Repository Live
Gene Summary
Gene Symbol
Cd2
Model Description
Validation Data
Fig1. Detection of CD2 expression in thymus and spleen by RT-PCR.
Wild type: only one band at 432 bp with primers F1/R1(mCd2);
Heterozygous: one band at 432 bp with primers F1/R1(mCd2) and one band at 228 bp with primers F2/R2(hCD2).
Abbr. M, DNA marker; HE, heterozygous; WT, wild type.
Fig2. Detection of CD2 expression on T cells, B cells and NK cells in spleen of WT C57BL/6 mice and HO hCD2 mice by FACS.
Leukocytes were collected from spleen of wild-type C57BL/6 mice (female, 7 weeks old) and homozygous hCD2 humanized mice (female, 7 weeks old), and analyzed by flow cytometry with anti-mCD2 and anti-hCD2.
Abbr. HO, homozygous; WT, wild type.
Fig3. Detection of CD2 expression on T cells, B cells and NK cells in blood of WT C57BL/6 mice and HO hCD2 mice by FACS.
Leukocytes were collected from blood of wild-type C57BL/6 mice (female, 7 weeks old) and homozygous hCD2 humanized mice (female, 7 weeks old), and analyzed by flow cytometry with anti-mCD2 and anti-hCD2.
Abbr. HO, homozygous; WT, wild type.
You may also like
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreWorkshop：Progress and Advances in Preclinical immuno-Oncology Research
SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn moreCustomizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more
