Trp53-KO

Nomenclature

B6.129-Trp53tm1Smoc

Cat. NO.

NM-KO-00011

Strain State

Embryo Cryopreservation

Export PDF

Gene Summary

Gene Symbol
Trp53

Synonyms

bbl; bfy; bhy; p44; p53; Tp53

NCBI ID

22059

MGI ID

98834

Ensembl ID

ENSMUSG00000059552

Pubmed

Trp53

Human Ortholog

TRP53

Model Description

A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.
Research Application：Tumorigenesis，aging，antineoplastic drug evaluation etc

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more