Ighm-KO
Nomenclature
C57BL/6JSmo-Ighmem1Smoc
Cat. NO.
NM-KO-18024
Strain State
Embryo Cryopreservation
Gene Summary
Gene Symbol
Ighm
Model Description
Validation Data
Generation strategy
Fig.1 Schematic diagram for the Ighm-KO mice generation strategy.
Ighm mRNA expression
Fig.2 Expression of Ighm mRNA in the blood and spleen tissue of WT and KO mouse strains. The result shows that Ighm was not detected in blood and spleen of Ighm-KO homozygous mice.
FACS validation of IgM knockout
Fig.3 t. FACS analysis of CD45+ cells from WT and Ighm-KO mice. The result shows that Ighm was not detected in splenocytes ,lymphocytes and bone morrow cells of Ighm-KO mice.
You may also like
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreWorkshop：Progress and Advances in Preclinical immuno-Oncology Research
SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn moreCustomizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more
