Cells

We have established a primary tumor cell bank derived from spontaneous tumors in mice, which can be used for genetic function studies, drug testing, and efficacy evaluation.

Animal Model (These include, but are not limited to, the following data.)

Strain State (Con:Construction; Expr:Validation of target gene expression; TC:Validation of tumorigenic capacity; Parma:Validation of pharmacodynamic assays.)

Cell Line
Cancer Type
Category
Organism
Animal Model
Strain State
Con
Expr
TC
Parma
hHER2*ex20ins-IRES-Luc-2A-EGFP Breast Cancer Primary Mus musculus
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KPC Pancreatic Cancer Primary Mus musculus C57BL/6
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KPC(R270H) Pancreatic Cancer Primary Mus musculus
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KPC-Luc Pancreatic Cancer Reporter-labeled Mus musculus
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KPC-OVA-Luc Pancreatic Cancer Others Mus musculus
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KrasG12D/Mki67-e(2A-tdtomato-2A-AKaluciferase) lung cancer Primary Mus musculus
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LKB1-KO/Kras-G12D-Luc lung cancer Primary Mus musculus
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R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272/Alb-Cre-Tg Liver Cancer Primary Mus musculus
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R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c) lung cancer Primary Mus musculus
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Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP lung cancer Primary Mus musculus
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