Top2a-IRES-CreERT2

Nomenclature

C57BL/6JSmo-Top2aem1(IRES-CreERT2)Smoc

Cat. NO.

NM-KI-234071

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Top2a

Model Description

The IRES-CreERT2 expression cassette was knocked into the Top2a gene stop codon site.

Validation Data


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Fig1. CreERT2 mediated recombination in uterus of Top2a CreERT2/+;Rosa26 tdTomato/+ mice.

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Fig2. Detection of tdTomato(red) in various tissues of Top2a CreERT2+; Rosa26 tdTomato/+ mouse. 

Following tamoxifen induction, tdTomato expression was observed in the brain, spinal cord, eyeballs, heart, lungs, liver, stomach, salivary glands, skin, muscle, kidneys, large intestine, small intestine, spleen, pituitary gland, ovaries, thymus, uteruses, and adrenal glands. In the uninduced group, low expression of tdTomato was detected in the lungs, liver, stomach, salivary glands, skin, kidneys, large intestine, small intestine, spleen, pituitary gland, ovaries, thymus, uteruses, and adrenal glands.(80-days old, female) (For more detailed information please contact our technical advisor.) 




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