hNGF/hTNFa-Tg

Nomenclature

C57BL/6JSmo-Ngftm1(hNGF)Tgtn(hTNFa promoter-hTNFa-pA)Smoc

Cat. NO.

NM-XA-251928

Strain State

Sperm cryopreservation

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Model Description

The hNGF (NM-HU-241678) was crossed with hTNFa-Tg(NM-TG-200004) to generate hNGF/hTNFa-Tg mice.

Validation Data

image.png

Fig.1 Detection of human NGF (A) and  human TNFa expression (B) in serum of WT C57BL/6 mice (n=4, 2 females and 2 males, 8-10 weeks old) and hNGF/hTNFa-Tg mice (n=3, 1 female and 2 males, 10 weeks old) by ELISA. 

Abbr.  HO, homozygous; WT, wild type; N.D. not detected.

Note. Mice were injected intraperitoneally with LPS (5 mg/kg), and serum was collected at 2 h post-injection. 


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