pPdx1-Cre-Tg

Nomenclature

C57BL/6JSmo-Tgtn(Pdx1 promoter-Cre-hACTB 3’UTR-polyA)1Smoc

Cat. NO.

NM-TG-251935

Strain State

Repository Live

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Model Description

These transgenic mice harbor Pdx1 promoter-Cre-hACTB 3’UTR-polyA expression cassettes.

鉴定报告

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Validation Data

image.png

Fig.1 Detection of Pdx1 expression in pancreas by RT-PCR. Pancreas RNA was extracted from a 8-10-week-old male WT C57BL/6 mouse and a 28-week-old male pPdx1-Cre-Tg mouse, then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers. Mouse Gapdh mRNA (123 bp) was detectable both in the WT C57BL/6 mouse and the pPdx1-Cre-Tg mouse. Mouse Pdx1 mRNA (113 bp) and iCre coding sequence (134 bp) were detectable only in the pPdx1-Cre-Tg mouse but not in the WT mice. 

Abbr. M, marker; WT, wild type.


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