hMAG

Nomenclature

C57BL/6JSmo-Magtm1(hMAG)Smoc

Cat. NO.

NM-HU-241955

Strain State

Repository Live

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Gene Summary

Gene Symbol
Mag

Model Description

The endogenous mouse Mag gene was replaced by human MAG gene.

Validation Data

5251cda2-06a1-4fa7-a3e6-bdb728928aeb.png

Fig.1 Detection of MAG expression in brain by RT-PCR. Brain RNA was extracted from 7-week-old male wild-type C57BL/6 (WT)(n=3) and homozygous hMAG knockin mice (HO) (n=3), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers. 

Abbr. M, marker; HO, homozygous; WT, wild type.

e0b7c567-e293-45ea-93f2-788a9bae48b0.png

Fig.2 Detection of human MAG (A) and mouse MAG(B) expression in brain homogenate of WT C57BL/6 mice and HO hMAG mice by ELISA.  

Brain homogenate were collected from wild-type C57BL/6 mice (n=3, male, 6 weeks old) and HO hMAG mice (n=3, male, 7 weeks old), and analyzed by ELISA with anti-hMAG ELISA kit  and anti-mMAG ELISA kit. 

Abbr.  HO, homozygous; WT, wild type; N.D. not dected.


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