hCD300A
Nomenclature
C57BL/6JSmo-Cd300atm1(hCD300A)Smoc
Cat. NO.
NM-HU-241971
Strain State
Embryo Cryopreservation
Gene Summary
Gene Symbol
Cd300a
Model Description
Validation Data
Fig.1 Expression analysis of hCD300A on B cells, CD4+T cells, CD8+T cells, and NK cells in spleen of hCD300A humanized mice.
Leukocytes were collected from spleen of wild-type C57BL/6 mice (male, 20 weeks old) and homozygous hCD300A mice (male, 20 weeks old), and analyzed by flow cytometry with anti-mCD300A and anti-hCD300A. hCD300A was exclusively detectable in hCD300A humanized mice but not in wild-type mice.
Fig.2 Expression analysis of hCD300A on B cells, CD4+T cells, CD8+T cells, and NK cells in blood of hCD300A humanized mice.
Leukocytes were collected from blood of wild-type C57BL/6 mice (male, 20 weeks old) and homozygous hCD300A mice (male, 20 weeks old), and analyzed by flow cytometry with anti-mCD300A and anti-hCD300A. hCD300A was exclusively detectable in hCD300A humanized mice but not in wild-type mice.
Fig.3 Expression analysis of hCD300A on monocytes, neutrophils, macrophages, and DCs in spleen of hCD300A humanized mice.
Leukocytes were collected from spleen of wild-type C57BL/6 mice (male, 20 weeks old) and homozygous hCD300A mice (male, 20 weeks old), and analyzed by flow cytometry with anti-mCD300A and anti-hCD300A. hCD300A was exclusively detectable in hCD300A humanized mice but not in wild-type mice.
Fig.4 Expression analysis of hCD300A on monocytes, neutrophils, macrophages in blood of hCD300A humanized mice.
Leukocytes were collected from blood of wild-type C57BL/6 mice (male, 20 weeks old) and homozygous hCD300A mice (male, 20 weeks old), and analyzed by flow cytometry with anti-mCD300A and anti-hCD300A. hCD300A was exclusively detectable in hCD300A humanized mice but not in wild-type mice.
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