R26-CAG-hPNPLA3-I148M-EGFP

Nomenclature

C57BL/6JSmo-Gt(ROSA)26Sortm1(SA-Frt-2xpolyA-CAG-Frt-LSL-PNPLA3 I148M-IRES-GFP-wpre-polyA)Dppa3tm1(IRES-Cre)Smoc

Cat. NO.

NM-XA-242479

Strain State

Repository Live

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Model Description

The R26-CAG-LSL-hPNPLA3*I148M-EGFP(NM-KI-200013) was crossed with Dppa3-IRES-Cre(NM-KI-00040) to generate R26-CAG-LSL-hPNPLA3*I148M-EGFP/Dppa3-IRES-Cre mice.

Validation Data

image.png

Fig.1 Detection of PNPLA3 expression in liver, lung, WAT, BAT by qPCR. Each value in liver, lung, WAT, BAT represents the mRNA level relative to the value in liver (n=2).

image.png

Fig.2 Detection of human PNPLA3 expression by WB. 

Abbr. M, marker; WT, wild type; HE, heterozygous.

Note. Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.



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