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Humanized Metabolic Pharmacodynamics Research Model

Humanized metabolic pharmacodynamics research models are mouse models generated by inserting human metabolic-related genes or protein targets into the mouse genome using gene editing technology. These models have significant application value in the research and development of metabolic drugs.

Popular Humanized Models for Metabolic Pharmacodynamics Research

hGLP1R

hGIPR

hINHBE

hANGPTL3

More Humanized Models for Metabolic Pharmacodynamics Research

Cat. NO.	Strain name	Specimen Name	Strain State
NM-HU-233513	hCIDEB	C57BL/6JSmo-Cideb^tm1(hCIDEB)^Smoc	Repository Live
NM-HU-215016	hCYP2D	C57BL/6JSmo-Cyp2d^{tm(hCYP2D)Smoc}	Embryo Cryopreservation
NM-HU-215024	hCYP2D6	C57BL/6JSmo-Cyp2d^{tm(hCYP2D6)Smoc}	Sperm cryopreservation
NM-HU-210007	hFAS	C57BL/6JSmo-Fas^{tm1(hTNFRSF6)Smoc}	Sperm cryopreservation
NM-HU-232149	hFGFR3-G380R	C57BL/6JSmo-Fgfr3^{tm1(hFGFR3-G380R)}^Smoc	Repository Live
NM-HU-220418	hFOLR1	C57BL/6JSmo-Folr1^{tm(hFOLR1)Smoc}	Repository Live
NM-HU-215004	hGCGR	C57BL/6JSmo-Gcgr^{tm(hGCGR)Smoc}	Repository Live
NM-HU-233747	hGCGR/hGLP1R	C57BL/6JSmo-Gcgr^tm(hGCGR)Glp1r^tm2(hGLP1R)^Smoc	Repository Live
NM-HU-225064	hGIPR	C57BL/6JSmo-Gipr^{tm2(hGIPR)Smoc}	Repository Live
NM-HU-200220	hGLP1R	C57BL/6JSmo-Glp1r^{tm2(hGLP1R)Smoc}	Repository Live

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