Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

Mouse	Tcf4-A613V Strain Name：C57BL/6JSmo-Tcf4^{em(A613V)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-220388
Mouse	Tcf4-G502S/G508S/G518S Strain Name：C57BL/6JSmo-Tcf4^{em(QGQSVSSGSSEIKSDDEGD502-518QSQSVSSSSSEIKSDDESD)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-220595
Mouse	Tlr7-Y264H Strain Name：C57BL/6JSmo-Tlr7^{em(Y264H)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-230071
Mouse	Tm6sf2-E167K Strain Name：C57BL/6JSmo-tm6sf2^{em1(E167K)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-200002 Research Application：Myocardial infarction and total cholesterol related
Mouse	Tmem173-V154M Strain Name：C57BL/6JSmo-Tmem173^{em(V154M)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-225039 Research Application：STING-associated vasculopathy with onset in infancy (SAVI)
Mouse	Tnnt2-R158W Strain Name：C57BL/6JSmo-Tnnt2^em2R158W^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-233285
Mouse	Tph1-R251X Strain Name：C57BL/6JSmo-Tph1^em1(R251X)^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-232088
Mouse	Trap1-K128Q Strain Name：C57BL/6JSmo-Trap1^{em1(K128Q)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-210091
Mouse	Trap1-K128R Strain Name：C57BL/6JSmo-Trap1^{em1(K128R)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-210090
Mouse	Trap1-K128T Strain Name：C57BL/6JSmo-Trap1^{em1(K128T)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-210089

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