Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

Mouse	Trem2-R47H Strain Name：C57BL/6JSmo-Trem2^{em3(p.R47H)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-190092 Research Application：Neurobiology Research,Alzheimer's disease related
Mouse	Trem2-R62H Strain Name：C57BL/6JSmo-Trem2^{em1(R62H)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-210225
Mouse	Trex1-D18N Strain Name：C57BL/6JSmo-Trex1^em1D18N^Smoc Strain State：Repository Live \| Cat. NO.：NM-KI-231599
Mouse	Trp53-FSF-R270H Strain Name：C57BL/6JSmo-Trp53^{tm(Frt-Stop-Frt-R270H)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-210364
Mouse	Trp53-LSL-R270H Strain Name：C57BL/6JSmo-Trp53^{tm7(R270H-flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-200186 Research Application：Cancer research
Mouse	Trp53-R172H Strain Name：C57BL/6JSmo-Trp53^{em4(R172H)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-18028 Research Application：cancer research
Mouse	Trp53-R172H/Kras-LSL-G12D(2) Strain Name：C57BL/6JSmo-Trp53^em4(R172H)Kras^{em4(LSL-G12D)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-230388
Mouse	Trp53-R245W Strain Name：C57BL/6JSmo-Trp53^{em(R245W)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-225098
Mouse	Trp53-R270H Strain Name：C57BL/6JSmo-Trp53^{em3(R270H)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-18027 Research Application：cancer research
Mouse	Trpm2-D1066A Strain Name：C57BL/6JSmo-Trpm2^{em(D1066A)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-215101

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