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Models

Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

Mouse
Nphs2-A286V
Strain Name：C57BL/6JSmo-Nphs2em1(A286V)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-KI-200278
Disease Connection：hereditary glomerular disease
Mouse
Nphs2-R231Q
Strain Name：C57BL/6JSmo-Nphs2em1(R231Q)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200277
Disease Connection：hereditary glomerular disease
Mouse
Pah-R261Q
Strain Name：C57BL/6JSmo-Pahem(R261Q)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225102
Mouse
Pah-R408W
Strain Name：C57BL/6JSmo-Pahem(R408W)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225103
Mouse
Pde6b-R560C (Rd10)
Strain Name：C57BL/6JSmo-Pde6bem1R560CSmoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232201
Mouse
Pde6b-Y347* (Rd1)
Strain Name：C57BL/6JSmo-Pde6bem1Y347*Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232202
Mouse
Pgr-2A-Ikbkb*EE
Strain Name：C57BL/6JSmo-Pgrem(2A-Flag-Ikbkb*S177E/S181E)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220023
Mouse
Plcg2-P522R
Strain Name：C57BL/6JSmo-Plcg2em(P522R)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220042
Mouse
Pnpla3-I148M
Strain Name：C57BL/6JSmo-Pnpla3em1(I148M)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200185
Research Application：Non-alcoholic fatty liver disease
Mouse
Ptpn2-Y278C
Strain Name：C57BL/6JSmo-Ptpn2tm(Y278C)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225038
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