Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

Mouse
Strain Name:B6;129S-Mdm4tm1Smoc
Strain State:Embryo Cryopreservation | Cat. NO.:NM-KI-00007
Mouse
Strain Name:C57BL/6JSmo-Muc2em1C987YSmoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-234203
Mouse
Strain Name:C57BL/6JSmo-Mvdtm(F250S)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-210368
Mouse
Strain Name:C57BL/6JSmo-Myh6em1(R404Q)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-215054
Mouse
Strain Name:C57BL/6JSmo-Nagluem1(A198V)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-232081
Mouse
Strain Name:C57BL/6JSmo-Nagluem1(R531X)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-232082
Mouse
Strain Name:C57BL/6JSmo-Neflem1(N98S)Smoc
Strain State:Embryo Cryopreservation | Cat. NO.:NM-KI-200251
Disease Connection:Charcot-Marie-Tooth disease type 2E
Mouse
Strain Name:C57BL/6JSmo-Nlrp3tm(LSL-A350V)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-210365
Mouse
Strain Name:C57BL/6JSmo-Notch3em1(R170C)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200254
Disease Connection:CADASIL 1
Mouse
Strain Name:C57BL/6JSmo-Npc1em1(I1060T)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-18059
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