Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

Mouse	hHBB-E7V Strain Name：C57BL/6JSmo-hHBB^tm1(E7V)^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-233577
Mouse	hMAPT-P301S Strain Name：C57BL/6JSmo-Mapt^{tm1(hMAPT-P301S)}^Smoc Strain State：Repository Live \| Cat. NO.：NM-KI-233262
Mouse	Ifng-del(162bp) Strain Name：C57BL/6JSmo-Ifng^{em1(162bp-del)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-210223
Mouse	Il6st-Y757F/V760A Strain Name：C57BL/6JSmo-Il6st^{em(Y757F-V760A)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-220045
Mouse	Ins2-C96Y Strain Name：C57BL/6JSmo-Ins2^{em3(C96Y)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-190096 Disease Connection：diabetes
Mouse	Jak2-Flox-V617F Strain Name：C57BL/6JSmo-Jak2^{tm1(Flox-V617F)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-210367
Mouse	Jak2-Flox-V617F(2) Strain Name：C57BL/6JSmo-Jak2^{em(flox-V617F)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-220009
Mouse	Kit-V831M Strain Name：C57BL/6JSmo-Kit^{em2(V831M)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KI-190023 Research Application：hematopoieticstem cell
Mouse	Kit-V831M(NOD-scid) Strain Name：NOD-Prkdc^scidKit^{em1(V831M)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-200316 Research Application：Hematopoieticstem cell
Mouse	Kras-LSL-G12D Strain Name：C57BL/6JSmo-Kras^{em4(LSL-G12D)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-190003 Disease Connection：squamous cell carcinoma, prostate cancer, pancreatic carcinoma, neurofibromatosis, pancreatic ductal adenocarcinoma, juvenile myelomonocytic leukemia, urinary bladder cancer, ovarian cancer

Items per page

U-GEMMs

Other Models

Model Customization

Supporting Solutions

Oncology Drug Efficacy Evaluation Platform

Metabolism Disease Evaluation Platform

Inflammation Disease Evaluation Platform

Neurological Disease Evaluation Platform

Cell Lines Service Platform

Ex vivo & In vitro Evaluation Service Platform

Toxicology/Pathology Service Platform

Resources

Support

SMOC

Models

Point Mutation Knockins

Animal Health

Health Report

Animal Welfare

How to order

Terms of Shipping

Privacy Statement

Terms of Use

Contact